What Are The Causes Of Horse Laryngeal Hemiplegia?

Horse laryngeal hemiplegia is a common disorder in horses that can cause difficulty breathing, increased fatigue, and an inability to exercise. It is estimated that up to 40% of horses are affected by the condition. This article will provide an overview of the anatomy of the larynx and its role in the development of horse laryngeal hemiplegia, discuss genetic predisposition and environmental factors associated with the disease, and discuss diagnosis and treatment options. With this knowledge, readers can gain a better understanding of how to reduce the risk of horse laryngeal hemiplegia and how to treat it if it does develop.

Anatomy of the Larynx and Its Role in Horse Laryngeal Hemiplegia

The larynx, or voice box, is a vital organ located in the neck of all mammals, including horses. It is responsible for producing vocalizations, as well as coordinating breathing and protecting the airway from foreign bodies. The anatomy of the horse larynx is composed of several components, each of which plays a role in the development of laryngeal hemiplegia.

Muscles of the Larynx

The larynx is composed of multiple muscle layers that are responsible for its function. The outermost layer is the cricothyroid muscle, which is responsible for lengthening and shortening of the vocal folds. The inner layer is the thyroarytenoid muscle, which is responsible for abduction and adduction of the vocal folds. The middle layer is the arytenoid muscle, which is responsible for opening and closing of the vocal folds.

Cartilages of the Larynx

The larynx is also composed of several cartilages, which provide structural integrity and stability to the organ. The largest cartilage is the arytenoid cartilage, which helps to support the vocal folds and the vocal process. The epiglottis is another cartilage that helps to protect the airway from foreign bodies. The cricoid cartilage also provides structural support to the larynx.

Function of the Larynx

The larynx is responsible for producing vocalizations, as well as coordinating breathing and protecting the airway from foreign bodies. It also provides support for the tongue and the hyoid bone. This allows for the production of sound and vocalizations, as well as the movement of food and air through the mouth and throat.

Role of the Larynx in Horse Laryngeal Hemiplegia

Horse laryngeal hemiplegia is an equine disorder characterized by paralysis of one side of the larynx. This leads to difficulty in breathing and vocalizing, as well as a decrease in performance. The exact cause of this disorder is not known, but anatomy of the larynx plays a key role in its development.

The cricothyroid muscle is responsible for lengthening and shortening of the vocal folds, and if this muscle is paralyzed, it can lead to difficulty in breathing and vocalizing. The arytenoid muscle is responsible for opening and closing of the vocal folds, and if this muscle is paralyzed, it can lead to difficulty in vocalizing. The epiglottis and the cricoid cartilage also provide structural support to the larynx, and if these are weakened, it can lead to difficulty in breathing and vocalizing.

These anatomical components of the larynx are essential for normal functioning, and any disruption to these components can result in laryngeal hemiplegia. Therefore, it is important to understand the anatomy of the larynx and its role in horse laryngeal hemiplegia in order to diagnose and treat this disorder.

Genetic Predisposition to Horse Laryngeal Hemiplegia

Horse laryngeal hemiplegia, also known as “roaring”, is a disorder of the larynx (voice box) that affects horses. It is caused by a paralysis of the left or right recurrent laryngeal nerve, which results in a partial paralysis of the larynx. Research has shown that there is a genetic predisposition for horses to develop this disorder.

The genetic mutation associated with this disorder has been identified by researchers. It is a mutation in the CNTNAP2 gene, which is responsible for controlling the functioning of the recurrent laryngeal nerve. The mutation results in a disruption of the normal functioning of the nerve, leading to paralysis.

Studies have shown that certain breeds of horses are more likely to carry the genetic mutation. These breeds include the Thoroughbred, Andalusian, Arabian, and Lipizzaner. Other breeds, such as the Quarter Horse and Paint Horse, have been found to have a lower risk of carrying the mutation.

In addition to the breeds mentioned, there is also research that suggests that certain family lines of horses may be more prone to developing the disorder. For example, a study conducted by the University of Kentucky found that certain family lines of Thoroughbreds are more likely to carry the genetic mutation associated with laryngeal hemiplegia.

The genetic mutation associated with laryngeal hemiplegia is not the only factor that can increase the risk of a horse developing the disorder. Other factors, such as environmental and nutritional conditions, can also contribute to the development of laryngeal hemiplegia.

It is important to keep in mind that even if a horse has the genetic mutation, it does not necessarily mean that the horse will develop the disorder. Additionally, a horse may develop the disorder even if it does not have the mutation. Therefore, it is important to be aware of the environmental and nutritional factors that can contribute to the development of the disorder and take the necessary steps to reduce the risk.

Environmental Factors that Increase Risk of Horse Laryngeal Hemiplegia

There are certain environmental factors that can increase the risk of a horse developing laryngeal hemiplegia. These include:

Exposure to Dust and Pollutants

Horses that are exposed to high levels of dust and pollutants in the air, such as from industrial sites, can be at a higher risk of developing laryngeal hemiplegia. This is due to the inhalation of the particles, which can irritate the airway and lead to inflammation.

Exercise

Horses that are regularly exercised, particularly those that are involved in strenuous activities, are at a higher risk of developing laryngeal hemiplegia. This is because the increased breathing rate can place extra stress on the larynx and cause it to become inflamed.

Temperature

Hot and humid environmental conditions can also increase the risk of laryngeal hemiplegia in horses. This is because the warm air can cause the airway to become swollen and more prone to inflammation.

Stress

Stressful conditions, such as when horses are transported or moved to a new environment, can also increase the risk of laryngeal hemiplegia. This is because the stress can cause the larynx to become inflamed and more prone to the condition.

Age

Older horses are also more likely to develop laryngeal hemiplegia, as the airway can become more easily irritated and inflamed with age.

Breed

Certain horse breeds are more prone to developing laryngeal hemiplegia than others. These include Thoroughbreds, Arabians, and Standardbreds.

Diagnosis and Treatment of Horse Laryngeal Hemiplegia

Horse laryngeal hemiplegia (also known as "roaring," "broken wind," and "harsh-wind") is a common disorder of the larynx that is observed in horses. It is caused by paralysis of one side of the larynx, usually the left side. The condition can be congenital or acquired and is often characterized by a loud, rough, whistling sound when the horse breaths.

Diagnosis

The diagnosis of horse laryngeal hemiplegia is typically based on the horse’s clinical signs, physical examination, and imaging methods such as videoendoscopy or radiography. Videoendoscopy is considered the gold standard for diagnosis, as it provides an excellent visual examination of the larynx and allows the veterinarian to assess the airway and any abnormalities. It is also useful for monitoring the response to treatment. Additionally, radiography can be used to assess the size and shape of the larynx and the presence of any narrowing of the airway due to the condition.

Treatment

The treatment of horse laryngeal hemiplegia is aimed at improving the horse’s breathing and reducing the whistling sound. Treatment options include medical management, surgical procedures, and/or a combination of both.

Medical Management
Medical management typically involves the use of medications to reduce inflammation, reduce spasms, and improve airway patency. Commonly used medications include anti-inflammatories, bronchodilators, muscle relaxants, and corticosteroids.

Surgical Procedures
Surgical procedures for the treatment of horse laryngeal hemiplegia include laryngoplasty, or the surgical widening of the larynx, and arytenoid lateralization, which is the removal of a small piece of cartilage from the affected side of the larynx. Both of these procedures can be used to improve the horse’s breathing and reduce the whistling sound.

Prognosis
The prognosis for horses with laryngeal hemiplegia is generally good with appropriate treatment. However, the condition can recur and the horse may require ongoing medical management and/or additional surgical procedures.

Summary

The horse larynx is a vital organ located in the neck and composed of multiple muscles and cartilages that play an important role in producing vocalizations, coordinating breathing, and protecting the airway. These components can affect the development of laryngeal hemiplegia when they are not functioning properly. The cricothyroid muscle modulates vocal fold length; the thyroarytenoid muscle controls abduction/adduction movement; while,the arytenoid muscle produces opening/closing movements. Lastly, several cartilages provide structure to support these muscular functions.